arthritis, glucosamine, chondroitin

Arthritis - OA - RA : Causes & Treatments

"Arthritis ~ Osteoarthritis - Rheumatoid Arthritis ~ Frequently Asked Questions"

Click on the links below.....
What is Arthritis? What is Glucosamine? What does it do? What is MSM? What does it do?
What is Osteoarthritis? What is Chondroitin? What does it do? What is Arthiticare? How safe and effective is it?
What is Rheumatoid Arthritis? What is CMO? What does it do? Why Transdermal delivery?

What Is Arthritis?
There are many different kinds of arthritis, but the 2 most common types are osteoarthritis and rheumatoid arthritis. Osteoarthritis is the most common type of arthritis, and rheumatoid arthritis is the second most common.
What is osteoarthritis?
Osteoarthritis (OA) is a condition that can result from wear and tear on the joints, like the knees, hips and fingers, or from an injury. Many people may have only mild discomfort. But as cartilage covering the ends of bones in the joints wears away, many people may have considerable pain, inflammation, and loss of movement. OA occurs more often as people grow older and is the most common joint disease. About one third of people over age 35 show some signs of OA when they have x-rays. In addition to aging, other risk factors for OA include being overweight, injuries, and diabetes.
What is rheumatoid arthritis?
The main symptom of rheumatoid arthritis (RA) is inflammation—redness, heat, and pain—at the joints. RA affects the joint membranes, cartilage, and bones the way OA does. But unlike OA, RA can also affect the whole body—with loss of appetite, a general feeling of being unwell, and other symptoms. RA takes very different forms in different people. Some people have only a mild form of RA that does not get more severe. Others go on to develop severe deformities of the joints. Most people with RA fall somewhere in between. RA is usually first noticed in the small joints of the hands, feet, and wrists. It may then move on to the larger joints — elbows, shoulders, and knees. As RA gets worse, the joints can become deformed and too stiff to move. RA affects about 1 in every 100 people. It affects women 3 times more often than men. The people most likely to develop RA are those between the ages of 35 and 50.


Glucosamine

Is made up of glucose and glutamine, substances used naturally by the body to keep cartilage moist and pliant. Glucosamine plays a vital role in the structuring of healthy bone, cartilage, and other tissues. Glucosamine is also one of the nutrients that form the cushioning ingredients in the fluids of the joints and surrounding tissues.
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Chondroitin Sulfate
Appears to work together with Glucosamine, in both practical and in clinical trials, to help build new cartilage and resolve the underlying condition associated with redness and swelling. When these nutrients, found naturally in the joints, are not sufficiently available to the body, associated joint problems often result.

CMO (cis-9-cetylmyristoleate)
The discovery of cis-9-cetylmyristoleate in 1994, has been hailed by medical researchers like Dr. Harry Diehl of the National Institute of Health as "one of the most important discoveries this century in treating joint and cartilage problems." The active ingredients in CMO are wholly derived from 100% natural bovine food sources. When used for joint support, in a randomized clinical trial, cetyl myristoleate achieved an astounding 87.3% response when taken with glucosamine and hydrolyzed cartilage (as formulated in ArthritiCare).

MSM
Methyl-sulfonyl-methane is a naturally-occurring dietary sulfur compound found in all living things. Medical research indicates that MSM can offer men and women benefits that include Anti-inflammatory and pain relief to help with joint function. It improves your natural defenses against allergies and environmental toxins. As an immune system ‘normalizer’ it helps undo the source of many health problems and diseases.
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What is Arthriti-care? How safe and effective is it?
Arthiti-Care is a uniquely formulated safe and effective cream for treatment of both inflammation as well as cartilage repair in the case of Osteoarthritis and Rheumatoid arthritis. Its main ingredients are Glucosamine, Chondroitin Sulfate, CMO and MSM - delivered transdermally to the joints. Together they form an extremely effective therapy, that is safe and without adverse side effects.

But don't take our word for it. Below are summaries of clinical trials of some of the ingredients in Arthiti-care.

Glucosamine and Chondroitin Sulfate - clinical trials summary:
"An analysis of clinical trials on glucosamine and chondroitin sulfate for treating osteoarthritis has shown that these compounds have some efficacy against the symptoms of this form of arthritis.
The study, by Timothy E. McAlindon, DM, and colleagues at the Boston University School of Medicine, located 37 studies of the compounds in osteoarthritis by a thorough review of the scientific literature published over more than three decades.
Based on data from the trials, the researchers calculated an overall "effect size" for the two compounds: the figure 0.2 is considered a small effect; 0.5, moderate; and 0.8, large. The researchers calculated an effect size for glucosamine of 0.44 and for chondroitin sulfate of 0.78..."**

** The study was published in the March 15, 2000, issue of the Journal of the American Medical Association (JAMA).
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CMO (cetylmyristoleate) - clinical trials summary:
The effect of cetylmyristoleate on joints was published in Journal of Pharmaceutical Sciences [83(3):296-298]. It works as an immuno-modulator serving to repair the body's auto-immune disorder which is the common cause of arthritis.

Below are extracts from San Diego Clinic Immunological Center Clinical Study On Cetylmyristoleate (CMO) vs Arthritis - both Osteo and Rheumatoid Arthritis:
1.
Dosage level requirements appear to be equal irrespective of the severity of the subjects condition.
2. The time for maximum attainable response appears to vary from seven to twenty one days, resulting in 70% to 100% overall improvement.

(Click to review complete clinical study)

Why Transdermal delivery?
In the case of natural supplements as well as many medications, it is important to first understand why we feel strongly about transdermal delivery - absorbing nutrients through the skin. Doctors around the world are calling transdermal delivery "the delivery system of the future." It has been discovered that a high absorption rate of many supplements can be achieved when delivered through the skin - usually as a cream. (The physical size of the supplement's molecule plays an important role). The reason for this is when supplements are delivered transdermally, they go directly to the blood-stream, initially bypassing the liver. The result can mean as much as 95% of the supplements get to the cells where they are needed.* Conversely, studies have shown when some substances are taken orally, as little as 5% make it to the cells where they are needed. This is because of the stomach, liver and digestive system excreting and discarding much of them.
* Source: Department of Pharmacology, University of Dublin

Click here to learn more about Transdermal drug delivery.


Efficacy....Safety....Quality
Effective Health Products, Hillsborough, NJ USA
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