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What
Is Arthritis?
There are many different kinds of arthritis,
but the 2 most common types are osteoarthritis and rheumatoid arthritis.
Osteoarthritis is the most common type of arthritis, and rheumatoid arthritis
is the second most common.
What
is osteoarthritis?
Osteoarthritis (OA) is a condition that can result
from wear and tear on the joints, like the knees, hips and fingers, or
from an injury. Many people may have only mild discomfort. But as cartilage
covering the ends of bones in the joints wears away, many people may have
considerable pain, inflammation, and loss of movement. OA occurs more
often as people grow older and is the most common joint disease. About
one third of people over age 35 show some signs of OA when they have x-rays.
In addition to aging, other risk factors for OA include being overweight,
injuries, and diabetes.
What is rheumatoid arthritis?
The main symptom of rheumatoid arthritis (RA) is
inflammation—redness, heat, and pain—at the joints. RA affects the joint
membranes, cartilage, and bones the way OA does. But unlike OA, RA can
also affect the whole body—with loss of appetite, a general feeling of
being unwell, and other symptoms. RA takes very different forms in different
people. Some people have only a mild form of RA that does not get more
severe. Others go on to develop severe deformities of the joints. Most
people with RA fall somewhere in between. RA is usually first noticed
in the small joints of the hands, feet, and wrists. It may then move on
to the larger joints — elbows, shoulders, and knees. As RA gets worse,
the joints can become deformed and too stiff to move. RA affects about
1 in every 100 people. It affects women 3 times more often than men. The
people most likely to develop RA are those between the ages of 35 and
50.
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Glucosamine
Is made up of glucose and glutamine, substances
used naturally by the body to keep cartilage moist and pliant. Glucosamine
plays a vital role in the structuring of healthy bone, cartilage, and
other tissues. Glucosamine is also one of the nutrients that form the
cushioning ingredients in the fluids of the joints and surrounding tissues.
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Chondroitin
Sulfate
Appears to work together with Glucosamine,
in both practical and in clinical trials, to help build new cartilage
and resolve the underlying condition associated with redness and swelling.
When these nutrients, found naturally in the joints, are not sufficiently
available to the body, associated joint problems often result.
CMO
(cis-9-cetylmyristoleate)
The discovery of cis-9-cetylmyristoleate
in 1994, has been hailed by medical researchers like Dr. Harry Diehl of
the National Institute of Health as "one of the most important discoveries
this century in treating joint and cartilage problems." The active ingredients
in CMO are wholly derived from 100% natural bovine food sources. When
used for joint support, in a randomized clinical trial, cetyl myristoleate
achieved an astounding 87.3% response when taken with glucosamine and
hydrolyzed cartilage (as formulated in ArthritiCare).
MSM
Methyl-sulfonyl-methane is a naturally-occurring
dietary sulfur compound found in all living things. Medical research indicates
that MSM can offer men and women benefits that include Anti-inflammatory
and pain relief to help with joint function. It improves your natural
defenses against allergies and environmental toxins. As an immune system
‘normalizer’ it helps undo the source of many health problems and diseases.
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What
is Arthriti-care? How safe and effective is it?
Arthiti-Care
is a uniquely formulated safe and effective cream for treatment of both
inflammation as well as cartilage repair in the case of Osteoarthritis
and Rheumatoid arthritis. Its main ingredients are Glucosamine,
Chondroitin Sulfate, CMO and MSM - delivered transdermally
to the joints. Together they form an extremely effective therapy, that
is safe and without adverse side effects.
But
don't take our word for it. Below are summaries of clinical trials of
some of the ingredients in Arthiti-care.
Glucosamine and Chondroitin
Sulfate - clinical
trials summary:
"An analysis of clinical trials
on glucosamine and chondroitin sulfate for treating osteoarthritis has
shown that these compounds have some efficacy against the symptoms of
this form of arthritis.
The study, by Timothy E. McAlindon, DM, and colleagues at the Boston University
School of Medicine, located 37 studies of the compounds in osteoarthritis
by a thorough review of the scientific literature published over more
than three decades.
Based on data from the trials, the researchers calculated an overall "effect
size" for the two compounds: the figure 0.2 is considered a small effect;
0.5, moderate; and 0.8, large. The researchers calculated an effect size
for glucosamine of 0.44 and for chondroitin sulfate of 0.78..."**
** The
study was published in the March 15, 2000, issue of the Journal of the
American Medical Association (JAMA).
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CMO (cetylmyristoleate)
- clinical trials summary:
The effect of cetylmyristoleate on
joints was published in Journal of Pharmaceutical Sciences [83(3):296-298].
It works as an immuno-modulator serving to repair the body's auto-immune
disorder which is the common cause of arthritis.
Below are extracts from San Diego Clinic Immunological Center Clinical
Study On Cetylmyristoleate (CMO) vs Arthritis - both Osteo and Rheumatoid
Arthritis:
1. Dosage
level requirements appear to be equal irrespective of the severity of
the subjects condition.
2. The time for maximum attainable response appears to vary from seven
to twenty one days, resulting in 70% to 100% overall improvement.
(Click
to review complete clinical study)
Why
Transdermal delivery?
In
the case of natural supplements as well as many medications, it is important
to first understand why we feel strongly about transdermal delivery -
absorbing nutrients through the skin. Doctors around the world are calling
transdermal delivery "the delivery system of the
future." It has been discovered that a high absorption rate of many
supplements can be achieved when delivered through the skin - usually
as a cream. (The physical size of the supplement's molecule plays an important
role). The reason for this is when supplements are delivered transdermally,
they go directly to the blood-stream, initially bypassing the liver. The
result can mean as much as 95% of the supplements get to the cells where
they are needed.* Conversely, studies have shown when some substances
are taken orally, as little as 5% make it to the cells where they are
needed. This is because of the stomach, liver and digestive system excreting
and discarding much of them.
* Source:
Department of Pharmacology, University of Dublin
Click
here to learn more about Transdermal drug delivery.
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